Beyond the current standard of care

We’re a clinical-stage company developing next-generation immunotherapies for leukaemia and solid tumours

Harnessing the power of CAR-T cell therapy

We develop both autologous and allogeneic approaches to improve outcomes in cancer treatment

At OneChain, we are building a diversified portfolio of CAR‑T cell candidates designed to tackle some of the most challenging forms of cancer. By combining innovative targeting strategies with adaptable cell platforms, our goal is to broaden the scope and reach of this promising technology, which offers high precision, long-lasting responses and the potential to overcome resistance in both haematological malignancies and solid tumours.

A robust pipeline built on innovation

CAR T cell candidates targeting high need blood cancers and solid tumours

Our pipeline includes five CAR‑T cell candidates developed to address unmet medical needs in both haematological malignancies and solid tumours — a field where CAR‑T therapies remain in early stages. With novel antigen combinations, dual‑targeting strategies and an allogeneic platform in development, we’re working to bring the benefits of cellular immunotherapy to broader patient populations.

OC-1

Relapsed/refractory cortical T ALL

Target: CD1a
Indication: T-ALL

OC-1d

Relapsed/refractory T ALL

Target: CD1a/PC-12
Indication: T-ALL

OC-2

Relapsed/refractory B ALL

Target: CD22
Indication: B-ALL

OC-3

Universal platform for CAR-T generation

Target: Allogenic
Indication: Any

OC-4

Treatment for glioblastoma multiforme

Target: IL13a2/OC-4.2
Indication: T-ALL

Latest news

Discover our most recent updates

  • This is a title 3

    November 7, 2025

  • This is a title 2

    November 7, 2025

  • This is a title

    December 11, 2024

Where research and innovation converge

We’re located at one of Europe’s leading biomedical hubs

Parc Científic de Barcelona. Cluster II,
C/Baldiri Reixac, 4-12 i 15, 08028 Barcelona